A GYS2/p53 negative feedback loop restricts tumor growth in HBV-related hepatocellular carcinoma
S.-L. Chen, C. Z. Zhang, L.-L. Liu, S.-X. Lu, Y.-H. Pan, C.-H. Wang, Y.-F. He, C.-S. Lin, X. Yang, D. Xie, J.-P. Yun
This paper identifies a GYS2/p53 negative feedback loop that suppresses tumor growth in HBV-related hepatocellular carcinoma by regulating glycogen metabolism and p53 activity.
bioRxiv · Jul 20, 2018Pathology