Author

S.-Y. Zhang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Approach:statistical model· 2 Approach:deep learning· 1

Frequent Co-Authors

J.-L. Casanova· 4 shared A. AMARA· 1 shared A. Bodansky· 1 shared A. Boulle· 1 shared A. Corneau· 1 shared A. F. Hansen· 1 shared A. F. Kung· 1 shared A. Magerus· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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4 shared papersImmunology

J.-L. Casanova

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Autoantibody discovery across monogenic, acquired, and COVID19-associated autoimmunity with scalable PhIP-Seq

S. E. Vazquez, S. A. Mann, A. Bodansky, A. F. Kung, Z. Quandt, E. M. N. Ferre, N. Landegren, D. Eriksson, P. Bastard, S.-Y. Zhang, J. Liu, A. Mitchell, C. Mandel-Brehm, B. Miao, G. Sowa, , J. L. DeRisi

This paper scales PhIP-Seq for autoantibody discovery across multiple autoimmune diseases and COVID19, enabling machine learning predictions and identification of disease-specific autoantigens.

bioRxiv · Mar 23, 2022Immunology

High arsenic levels increase activity rather than diversity or abundance of arsenic metabolism genes in paddy soils

S.-Y. Zhang, X. Xiao, S.-C. Chen, Y. Zhu, G.-X. Sun, K. T. Konstantinidis

This study shows high arsenic levels increase transcriptional activity of arsenic metabolism genes in paddy soils without significantly affecting their diversity or abundance.

bioRxiv · May 3, 2021Microbiology

A monocyte/dendritic cell molecular signature of SARS-CoV2-related multisystem inflammatory syndrome in children (MIS-C) with severe myocarditis

C. de Cevins, M. Luka, N. Smith, S. Meynier, A. Magerus, F. Carbone, V. Garcia Paredes, L. Barnabei, M. Batignes, A. Boulle, M.-C. Stolzenberg, B. P. Perot, B. Charbit, T. Fali, V. Pirabarakan, , Gras Leguen

The paper identifies a monocyte/dendritic cell gene signature in severe MIS-C with myocarditis, linked to NF-κB activity and cytokine signaling.

bioRxiv · Feb 23, 2021Immunology

SARS-CoV-2 induces human plasmacytoid pre-dendritic cell diversification via UNC93B and IRAK4

F. Onodi, L. Bonnet-Madin, L. Meertens, L. Karpf, J. Poirot, S.-Y. Zhang, c. picard, A. Puel, E. Jouanguy, Q. Zhang, J. LeGoff, J.-M. Molina, C. Delaugerre, J.-L. Casanova, A. AMARA, V. Soumelis

This study shows SARS-CoV-2 activates human plasmacytoid pre-dendritic cells (pDC) via UNC93B and IRAK4, leading to interferon and cytokine production.

bioRxiv · Jul 10, 2020Immunology

Varicella-zoster virus CNS vasculitis and RNA polymerase III gene mutation in identical twins

M. Carter-Timofte, A. F. Hansen, M. Mardahl, S. Fribourg, F. Rapaport, S.-Y. Zhang, J.-L. Casanova, S. R. Paludan, M. Christiansen, C. S. Larsen, T. H. Mogensen

The paper reports a rare POLR3F mutation in monozygotic twins with severe CNS VZV vasculitis, linking RNA polymerase III dysfunction to increased susceptibility to VZV infection.

bioRxiv · Jan 8, 2018Immunology