Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
7 papers
Recent·Most cited
E. Rackaityte, I. Proekt, H. S. Miller, A. Ramesh, J. F. Brooks, A. F. Kung, C. Mandel-Brehm, D. Yu, C. Zamecnik, R. Bair, S. E. Vazquez, S. Sunshine, C. L. Abram, C. A. Lowell, G. Rizzuto, , J. L. DeRisi
This paper validates a murine proteome-wide PhIP-seq library to identify autoantibody specificities in autoimmune disease models.
bioRxiv · Apr 7, 2023Immunology
S. E. Vazquez, S. A. Mann, A. Bodansky, A. F. Kung, Z. Quandt, E. M. N. Ferre, N. Landegren, D. Eriksson, P. Bastard, S.-Y. Zhang, J. Liu, A. Mitchell, C. Mandel-Brehm, B. Miao, G. Sowa, , J. L. DeRisi
This paper scales PhIP-Seq for autoantibody discovery across multiple autoimmune diseases and COVID19, enabling machine learning predictions and identification of disease-specific autoantigens.
bioRxiv · Mar 23, 2022Immunology
M. G. P. van der Wijst, S. E. Vazquez, G. C. Hartoularos, P. Bastard, T. Grant, R. Bueno, D. S. Lee, J. R. Greenland, Y. Sun, R. Perez, A. Ogorodnikov, A. Ward, S. A. Mann, K. L. Lynch, C. Yun, , C. R. Langelier
The paper examines IFN-I autoantibodies in critical COVID-19 patients through longitudinal single-cell analysis, revealing suppressed ISG-I responses in myeloid cells.
bioRxiv · Mar 9, 2021 · PreprintImmunology
C. Mandel-Brehm, M. L. Fichtner, R. Jiang, V. J. Winton, S. E. Vazquez, M. C. Pham, K. B. Hoehn, N. L. Kelleher, R. J. Nowak, S. H. Kleinstein, M. R. Wilson, J. L. DeRisi, K. C. OConnor
This study identifies elevated N-glycosylation in IgG variable regions in myasthenia gravis patients and shows it is not required for autoantigen binding.
bioRxiv · Mar 6, 2021Immunology
B. J. Laidlaw, L. Duan, Y. Xu, S. E. Vazquez, J. G. Cyster
The paper identifies Hhex and Tle3 as regulators of memory B cell differentiation through single-cell RNA-seq and CRISPR screening, showing their interaction and functional roles.
bioRxiv · Feb 25, 2020Immunology
S. E. Vazquez, E. M. N. Ferre, D. W. Scheel, S. Sunshine, B. Miao, C. Mandel-Brehm, Z. Quandt, A. Y. Chan, M. Cheng, M. S. German, M. S. Lionakis, J. L. DeRisi, M. S. Anderson
This study uses PhIP-Seq to identify novel autoantigens in APS1, linking specific autoantibodies to clinical phenotypes like ovarian insufficiency and intestinal dysfunction.
bioRxiv · Jan 20, 2020Immunology
B. D. O'Donovan, C. Mandel-Brehm, S. E. Vazquez, J. Liu, A. V. Parent, M. S. Anderson, T. Kassimatis, A. Zekeridou, S. L. Hauser, S. J. Pittock, E. Chow, M. R. Wilson, J. L. DeRisi
This study uses PhIP-Seq to identify epitopes of anti-Yo and anti-Hu autoantibodies in PND patients, revealing restricted antigenic patterns and potential biomarkers.
bioRxiv · Dec 20, 2018Immunology