RIF1-ASF1-mediated high-order chromatin structure safeguards genome integrity
Sumin Feng, Sai Ma, Kejiao Li, Shengxian Gao, Shaokai Ning, Jinfeng Shang, Ruiyuan Guo, Yingying Chen, Britny Blumenfeld, Itamar Simon, Qing Li, Rong Guo, Dongyi Xu
This study identifies ASF1 as a partner of RIF1 that promotes NHEJ by compacting chromatin and suppressing resection in BRCA1-deficient cells.
Nature Communications · Feb 17, 2022Peer-reviewedMolecular Biology