Author

Kejiao Li

City Of Hope National Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:DNA methylation· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Binghui SheniD· 3 shared Guojun ShiiD· 3 shared Yao Yan· 3 shared Yi LeiiD· 3 shared Yingying WangiD· 3 shared Yixing WangiD· 3 shared Li ZhengiD· 2 shared Mian ZhouiD· 2 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCell Biology

Binghui ShenORCID

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Author profile →

4 papers

Recent·Most cited

XPF mediates 3' flap processing for FEN1-independent Okazaki fragment maturation

Kejiao Li, Feng Yang, Yingying Wang, Guojun Shi, Yixing Wang, Yunhao Liu, Yao Yan, Yi Lei, Main Zhou, Haitao Sun, Li Zheng, Binghui Shen

This paper shows that XPF degrades 3' flaps in human cells when FEN1 is deficient, enabling Okazaki fragment maturation and preventing DNA damage.

Nucleic Acids Research · May 20, 2026Peer-reviewedCell Biology

PARP1-mediated 5' flap dynamics facilitate Okazaki fragment maturation

Guojun Shi, Yixing Wang, Yao Yan, Kejiao Li, Lingzhi Ma, Yi Lei, Yingying Wang, Nancy Manriquez, Mian Zhou, Shan Zha, Li Zheng, Binghui Shen

This study identifies context-dependent roles of PARP1 in regulating Okazaki fragment maturation by controlling 5' flap dynamics and DNA ligation processes.

bioRxiv · Apr 30, 2026 · PreprintMolecular Biology

JMJD1B-mediated FEN1 demethylation allows timely switching of Okazaki fragment maturation core enzymes to avoid mutagenic flap ligation by PARP1-LIG3

Yao Yan, Guojun Shi, Kejiao Li, Yi Lei, Yixing Wang, Yingying Wang, Songbai Liu, Anthony Fernandez, Tingting Zhou, Evan Wang, Mian Zhou, Yuan Hang, Zhuo Li, Zhigang Guo, Zheng Li, Binghui Shen

bioRxiv · Oct 6, 2025 · PreprintCell Biology

RIF1-ASF1-mediated high-order chromatin structure safeguards genome integrity

Sumin Feng, Sai Ma, Kejiao Li, Shengxian Gao, Shaokai Ning, Jinfeng Shang, Ruiyuan Guo, Yingying Chen, Britny Blumenfeld, Itamar Simon, Qing Li, Rong Guo, Dongyi Xu

This study identifies ASF1 as a partner of RIF1 that promotes NHEJ by compacting chromatin and suppressing resection in BRCA1-deficient cells.

Nature Communications · Feb 17, 2022Peer-reviewedMolecular Biology