Author

Sakshi Gorey

University of Freiburg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

Carlos Alfonso-GonzaleziD· 3 shared Judit CarrascoiD· 3 shared Mengjin Shi· 3 shared Valérie HilgersiD· 3 shared Dominika GrzejdaiD· 2 shared Fernando Mateos· 2 shared Hasan Can OzbulutiD· 2 shared Sarah Holec· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersMolecular Biology

Carlos Alfonso-GonzalezORCID

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3 papers

Recent·Most cited

Regulation of protein abundance in neurons by selective translation of 3'UTR isoforms

Sakshi Gorey, Hasan Can Ozbulut, Judit Carrasco, Ying Zhang, Anton Heß, Ipek Akol, Carlos Alfonso-Gonzalez, Mengjin Shi, Dominika Grzejda, Julian Wolter-Mess, Mirijam Egg, Fernando Mateos, Sarah Holec, Alejandro Gomez‐Auli, Nina Cabezas‐Wallscheid, , Valérie Hilgers

The paper shows that long 3'UTR isoforms in neurons are less efficiently translated than short ones, mediated by ELAV and Pumilio, and that disrupting this mechanism reduces viability and stress resilience.

bioRxiv · Jul 9, 2026 · PreprintMolecular Biology

Pumilio differentially binds to mRNA 3' UTR isoforms to regulate localization of synaptic proteins

Dominika Grzejda, Anton Hess, Andrew Rezansoff, Sakshi Gorey, Judit Carrasco, Carlos Alfonso-Gonzalez, Stylianos Tsagkris, Lena Neuhaus, Mengjin Shi, Hasan Can Ozbulut, F.‐Nora Vögtle, Andreas Vlachos, Valérie Hilgers

This study shows Pumilio binds different mRNA 3' UTR isoforms to regulate synaptic protein localization in Drosophila neurons.

EMBO Reports · Feb 21, 2025Peer-reviewedGenomics

ELAV mediates circular RNA biogenesis in neurons

Carlos Alfonso-Gonzalez, Mengjin Shi, Sakshi Gorey, Sarah Holec, Judit Carrasco, Michael Rauer, Stylianos Tsagkris, Fernando Mateos, Valérie Hilgers

This study shows ELAV regulates neuronal circRNA production by modulating splicing to favor circularization over linear splicing.

bioRxiv · Jun 22, 2024Molecular Biology