Andreas Vlachos

The paper investigates how the number of pulses in theta-burst magnetic stimulation affects synaptic plasticity in human cortical slices, finding that 900 pulses induce potentiation while 600 pulses do not.

This paper establishes an organotypic co-culture model to study long-range hippocampal-prefrontal connectivity and plasticity, showing preserved intrinsic properties and functional responses.

This study quantifies how VR headset geometry affects TMS coil placement and intensity compensation in DLPFC targeting, showing that some headsets exceed compensable distance limits.

This study shows that repeated rTMS induces microglia-dependent synaptic remodeling in pyramidal neurons, reducing synaptic strength and spine density.

This paper presents a Gaussian process-based method for optimizing TMS coil location and orientation to improve motor hotspot identification efficiency and precision.

This study shows that dual SHP2/MEK inhibition in pancreatic cancer causes mitochondrial changes and ROS elevation, leading to a therapy-resistant state that can be targeted with GPX4 inhibition.

This study identifies an iron-associated mesenchymal subpopulation in GBM that drives invasion and is linked to poor patient survival.

This study uses in vitro rMS and computational modeling to show that rTMS enhances synaptic plasticity through cooperative pre- and postsynaptic activity mediated by BDNF.

This study shows that iTBS600 induces long-term potentiation and structural changes in mouse brain slices, with direction-dependent effects and preserved network stability.

This paper investigates how homeostatic synaptic scaling and structural plasticity interact to maintain neural network firing rates under activity perturbations.

This study shows Pumilio binds different mRNA 3' UTR isoforms to regulate synaptic protein localization in Drosophila neurons.

This study introduces an optimization strategy for TMS-based motor mapping using farthest point sampling, showing it is more efficient and robust than random sampling.

The paper identifies Pantr1 as a lncRNA regulated by FOXG1 that facilitates FOXG1's site-specific chromatin binding and impacts neuronal development.

The paper develops a multi-scale model to simulate rTMS-induced synaptic plasticity in pyramidal neurons, showing frequency- and location-dependent changes in excitatory synapses.

This study shows that axon morphology and intrinsic cellular properties influence the intensity needed for rTMS to induce synaptic plasticity in rat versus mouse tissue cultures.

This study examines myelination patterns in FCD IIa and IIb in the frontal lobe, finding divergent maladaptive myelination features between the two subtypes.

The paper investigates microglial and astrocytic responses to a Schaffer collateral lesion and MMPs modulation in mouse hippocampal slice cultures, revealing region-specific changes.

This study shows that synaptopodin and the spine apparatus organelle are essential for lesion-induced synaptic plasticity at hippocampal mossy fiber synapses in mice.

This paper uses computational modeling to show that rTMS induces dose-dependent homeostatic structural plasticity in neuronal networks, influenced by stimulation parameters and inhibition.

This study shows antiepileptic drugs enhance excitatory neurotransmission in human neocortical pyramidal neurons through homeostatic synaptic plasticity.

This study investigates the role of amyloid precursor protein (APP) in synaptic transmission at medial perforant path synapses using organotypic cultures and finds that presynaptic APP affects neurotransmission efficacy.

This paper investigates the functional interactions between premotor and motor cortical areas in rats during goal-directed behavior, revealing differential roles of neuronal subpopulations in movement preparation and execution.

This study shows that TNF affects excitatory and inhibitory neurotransmission differently at low and high concentrations, with high concentrations activating microglia and inducing homeostatic effects.

This study shows that all-trans retinoic acid induces synaptopodin-dependent metaplasticity in mouse dentate granule cells without altering baseline synaptic transmission.

This study shows that 10 Hz rTMS induces synaptic plasticity via microglia-released cytokines, with TNF and IL6 playing a key role.

The paper introduces NeMo-TMS, a toolbox for simulating TMS-induced neuronal and subcellular responses across scales, enabling detailed modeling of TMS effects.

This study shows that amyloid-beta, not APP or its secreted fragments, mediates homeostatic synaptic plasticity in the absence of APP.

This study shows all-trans retinoic acid induces synaptic plasticity in human cortical neurons by causing structural and functional changes in excitatory synapses.

This paper reviews rTMS studies from 1991 to 2020, finding most use motor threshold intensity and lack sufficient detail to reproduce stimulation parameters.