Author

Sam Singer

Memorial Sloan Kettering Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Assay:ChIP-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Afroditi SotiriouiD· 1 shared Alvin Qiu· 1 shared Ana BanitoiD· 1 shared Angela Goytain· 1 shared Annaïck Carles· 1 shared Benjamin Alexander NaceviD· 1 shared Douglas BarrowsiD· 1 shared Edmund SuiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Afroditi SotiriouORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Synovial Sarcoma Chromatin Dynamics Reveal a Continuum in SS18:SSX Reprograming

Jakob Hofvander, Alvin Qiu, Kiera Lee, Misha Bilenky, Annaïck Carles, Qi Cao, Michelle Moksa, Jonathan Steif, Edmund Su, Afroditi Sotiriou, Angela Goytain, Lesley A. Hill, Sam Singer, Irene L. Andrulis, Jay S. Wunder, , Martin Hirst

This study examines the epigenomic states of synovial sarcoma using multi-omics analysis, revealing a continuum of epigenomic states and identifying H3K4me3 inhibition as a potential therapeutic strategy.

bioRxiv · May 14, 2024 · PreprintCancer Biology

ATRX guards against aberrant differentiation in mesenchymal progenitor cells

Fang Yan, Douglas Barrows, Yakshi Dabas, Thomas S. Carroll, Sam Singer, William D. Tap, Benjamin Alexander Nacev

This study shows that ATRX loss in mesenchymal progenitor cells leads to aberrant differentiation by altering chromatin structure and gene regulation.

Nucleic Acids Research · Mar 5, 2024Peer-reviewedGenetics