Extracellular vesicle bioactivity and potential clinical utility is determined by mesenchymal stromal cell clonal subtype
Savvas Ioannou, Alasdair G. Kay, Andrew P. Stone, Emma Rand, Samuel Elberfeld, William Bolton, Tony R. Larson, Rachel E. Crossland, Oksana Kehoe, David A. Mentlak, Xiao-Nong Wang, Chris MacDonald, Paul G. Genever
This study compares EV bioactivity and clinical utility from two clonal MSC subtypes, finding Y201 EVs show enhanced proliferation effects and in vivo efficacy compared to Y202 EVs.
Stem Cell Research & Therapy · Oct 16, 2025Peer-reviewedCell Biology