Simultaneous measurements of translation rate and transcriptome in single bacterial cells by scTR-seq uncovers linked regulation within a specialized active cell population.
Christopher T. Baumann, Molly A. Hydorn, Samuel F. Cooke, Jonathan E. Dworkin, Adam Z. Rosenthal
The paper measures translation rates and transcriptomes in single bacterial cells to identify a subpopulation with increased protein translation and specific gene overexpression under nutrient limitation.
bioRxiv · Apr 22, 2025 · PreprintMicrobiology