Author

Molly A. Hydorn

Columbia UniversityORCID 0000-0002-3881-0821Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:E. coli· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Jonathan E. DworkiniD· 2 shared Adam Z. RosenthaliD· 1 shared Caroline S. HarwoodiD· 1 shared Christopher T. BaumanniD· 1 shared Elizabeth M. FonesiD· 1 shared Samuel F. Cooke· 1 shared Sathya Narayanan NagarajaniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 12 mutual co-author links

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2 shared papersMicrobiology

Jonathan E. DworkinORCID

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2 papers

Recent·Most cited

MicrobiologyPLoS GeneticsPeer-reviewedAug 22, 2025

Analysis of (p)ppGpp metabolism and signaling using a dynamic luminescent reporter

Molly A. Hydorn, Sathya Narayanan Nagarajan, Elizabeth M. Fones…·Jonathan E. Dworkin

This paper develops a dynamic luminescent reporter to measure (p)ppGpp levels in Bacillus subtilis, revealing its role in gene regulation and metabolic responses to nutrient limitation.

7 citations

bacteria (other)experimental assay

𝕏 PostBluesky

MicrobiologybioRxivPreprintApr 22, 2025

Simultaneous measurements of translation rate and transcriptome in single bacterial cells by scTR-seq uncovers linked regulation within a specialized active cell population.

Christopher T. Baumann, Molly A. Hydorn, Samuel F. Cooke…·Adam Z. Rosenthal

The paper measures translation rates and transcriptomes in single bacterial cells to identify a subpopulation with increased protein translation and specific gene overexpression under nutrient limitation.

DOI 10.1101/2025.04.22.649982

E. coliscRNA-seq

𝕏 PostBluesky