An activation-based high throughput screen identifies caspase-10 inhibitors
José O. Castellón, Constance Yuen, Brandon Han, Katrina H. Andrews, Samuel Ofori, Ashley R. Julio, Lisa M. Boatner, Maria F. Palafox, Nithesh Perumal, Robert D. Damoiseaux, Keriann M. Backus
This study identifies caspase-10 inhibitors using an activation-based high-throughput screen, revealing inhibitors that preferentially target the zymogen form of caspase-10.
RSC Chemical Biology · Jan 1, 2025Peer-reviewedBiochemistry