Author

Maria F. Palafox

University of California, Los AngelesORCID 0000-0002-4752-953XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Keriann M. BackusiD· 2 shared Adam R. FergusoniD· 1 shared Ashley R. JulioiD· 1 shared Brandon Han· 1 shared Constance YueniD· 1 shared Debarag BanerjeeiD· 1 shared Fanny M. ElahiiD· 1 shared Francisco J. LoperaiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

Keriann M. BackusORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

An activation-based high throughput screen identifies caspase-10 inhibitors

José O. Castellón, Constance Yuen, Brandon Han, Katrina H. Andrews, Samuel Ofori, Ashley R. Julio, Lisa M. Boatner, Maria F. Palafox, Nithesh Perumal, Robert D. Damoiseaux, Keriann M. Backus

This study identifies caspase-10 inhibitors using an activation-based high-throughput screen, revealing inhibitors that preferentially target the zymogen form of caspase-10.

RSC Chemical Biology · Jan 1, 2025Peer-reviewedBiochemistry

Plasma Proteomics of Genetic Brain Arteriosclerosis and Dementia Syndrome Identifies Signatures of Fibrosis, Angiogenesis, and Metabolic Alterations

Jonah N. Keller, Hannah Radabaugh, Nikolaos Karvelas, Stephen Fitzsimons, Scott Treiman, Maria F. Palafox, Lisa McDonnell, Yakeel T. Quiroz, Francisco J. Lopera, Debarag Banerjee, Michael M. Wang, Joseph F. Arboleda-Velasquez, James F. Meschia, Adam R. Ferguson, Fanny M. Elahi

The paper identifies plasma proteomic signatures associated with CADASIL stages, revealing fibrosis, angiogenesis, and metabolic alterations.

bioRxiv · Mar 28, 2024 · PreprintNeuroscience

From Chemoproteomic-Detected Amino Acids to Genomic Coordinates: Insights into Precise Multi-omic Data Integration

Maria F. Palafox, Heta S. Desai, Valerie A. Arboleda, Keriann M. Backus

This study maps chemoproteomic-detected amino acids to genomic coordinates, revealing that reactive cysteine codons are enriched for deleterious genetic variants.

Molecular Systems Biology · Feb 1, 2021Peer-reviewedSystems Biology