Toxin-triggered activation of regulated exocytosis enhances bacterial egress from the intestinal layer
C. G. Margraf, Lilo Greune, Joyleen M Fernandes, Paweena Wessel, Samriti Sharma, Johanna Sibbel, Sandra Heissler, Christian Rüter, Petra Dersch
This study identifies a non-lytic egress pathway used by Yersinia pseudotuberculosis to exit intestinal epithelial cells via host exocytosis machinery, mediated by a CNF-family toxin.
bioRxiv · Feb 6, 2026 · PreprintMicrobiology