Joyleen M Fernandes

This paper shows that IpaH7.8, a Shigella effector, enters human cells without a secretion system, suppresses inflammasome activity, and reprograms kinase signaling to inhibit oxidative burst responses.

This study identifies a non-lytic egress pathway used by Yersinia pseudotuberculosis to exit intestinal epithelial cells via host exocytosis machinery, mediated by a CNF-family toxin.