Petra Dersch

This paper shows that IpaH7.8, a Shigella effector, enters human cells without a secretion system, suppresses inflammasome activity, and reprograms kinase signaling to inhibit oxidative burst responses.

This study identifies a non-lytic egress pathway used by Yersinia pseudotuberculosis to exit intestinal epithelial cells via host exocytosis machinery, mediated by a CNF-family toxin.

This paper investigates immune priming in the gut of Tribolium castaneum using RNA sequencing and transmission electron microscopy, showing that priming leads to gut damage, stress response, and gene upregulation that enhances protection against subsequent infection.

This study identifies T6SS4 as heterogeneously expressed in Y. pseudotuberculosis and reveals its regulation by transcriptional and post-transcriptional mechanisms.

This study shows that the spleen produces neutrophils with distinct differentiation trajectories during stress, which are functionally competent and necessary for host defense against bacterial infection.

This study identifies RNase III and PNPase as key regulators of virulence gene expression in Yersinia pseudotuberculosis by modulating lcrF mRNA stability and translation.

This paper examines how C. rodentium {phi}stx2dact infection and antibiotic treatment affect fecal microbiota in mice, finding that antibiotics causing rapid infection clearance have the most detrimental impact on microbiota diversity.