Author

Sandra Melo Carlos

Genentech

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 2 Approach:benchmark study· 1 Assay:imaging· 1 Research Focus:perturbation response prediction· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Benjamin B. ChuiD· 1 shared Berton A. EarnshawiD· 1 shared Conor A. TillinghastiD· 1 shared Diana Wu· 1 shared Imran S. HaqueiD· 1 shared Jack KammiD· 1 shared Jake YeungiD· 1 shared Jan-Christian HütteriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Benjamin B. ChuORCID

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Author profile →

2 papers

Recent·Most cited

Joint analysis of multiply perturbed cells improves statistical power and cost efficiency in Perturb-seq

Jake Yeung, Jenille Tan, Liang Wang, Diana Wu, Sandra Melo Carlos, Jorge Kageyama, Jack Kamm, Benjamin B. Chu, Oleg Mayba, William F. Forrest, Shiqi Xie

This paper improves Perturb-seq by analyzing guide multiplets, reducing costs and maintaining signal recovery.

bioRxiv · Jul 11, 2026 · PreprintGenomics

Building, Benchmarking, and Exploring Perturbative Maps of Transcriptional and Morphological Data

Safiye Çelik, Jan-Christian Hütter, Sandra Melo Carlos, Nathan H. Lazar, Rahul Mohan, Conor A. Tillinghast, Tommaso Biancalani, Marta M. Fay, Berton A. Earnshaw, Imran S. Haque

This paper builds and benchmarks perturbative maps of transcriptional and morphological data, demonstrating their utility for discovering new biology and highlighting the importance of standardized frameworks.

PLoS Computational Biology · Oct 1, 2024Peer-reviewedBioinformatics