eEF1A2 controls local translation and actin dynamics in structural synaptic plasticity
Mònica B. Mendoza, Sara Gutierrez, Raúl Ortiz, David F. Moreno, Maria Dermit, Martin Dodel, Elena Rebollo, Miquel Bosch, Faraz K. Mardakheh, Carme Gallego
This study shows that phosphorylation of eEF1A2 modulates local translation and actin dynamics, influencing structural synaptic plasticity through interactions with GEF proteins and metabotropic glutamate receptor signaling.
bioRxiv · Oct 20, 2020 · PreprintNeuroscience