Martin Dodel

The paper defines an RNA-centric landscape of human cell cycle control by profiling various RNA features and identifies key RNA elements involved in cell cycle regulation.

This study identifies a pre-rRNA positive feedback loop driven by CK2 in the nucleolus that promotes malignant ribosome biogenesis and cancer growth.

HCR-Proxy maps RNA-proximal proteomes at subcompartmental resolution, revealing sequence-encoded protein partitioning in nucleolar condensates.

This study identifies CoAsy as a regulator of HIF signalling in TNBC, showing its loss stabilizes HIF-1 and HIF-2 and correlates with poor patient outcomes.

This study identifies RSRC2 as a regulator of mitotic fidelity through its interaction with the lncRNA C1QTNF1-AS1, showing defects in chromosome congression when either is lost.

The paper systematically identifies post-transcriptional regulatory modules by integrating multimodal data on RBP interactions and functions.

This study shows STAG3 regulates post-transcriptional mRNA in mESCs, promoting exit from pluripotency by interacting with RNA-binding proteins and affecting mRNA stability.

This study shows KIS phosphorylates PTBP2, counteracting its role in exon exclusion and regulating alternative exon usage in neurons.

This study shows that phosphorylation of eEF1A2 modulates local translation and actin dynamics, influencing structural synaptic plasticity through interactions with GEF proteins and metabotropic glutamate receptor signaling.

The paper identifies RBMS1 as a suppressor of colon cancer metastasis by stabilizing its mRNA targets, showing its clinical relevance in patient survival.