MicrobiologyNature CommunicationsPeer-reviewed
The virulence regulator VirB from Shigella flexneri uses a CTP-dependent switch mechanism to activate gene expression
Sara Jakob, Wieland Steinchen, Juri Hanßmann…·Martin R. Thanbichler
This study shows VirB, a virulence regulator in Shigella flexneri, uses CTP binding and hydrolysis to control DNA binding and sliding, thereby regulating gene expression.
17 citations