Cationic charge and polyspecificity of an integrin domain regulates infectivity of malaria parasites
Dennis Klug, Sarah Goellner, Julia Sattler, Leanne Strauss, Jessica Kehrer, Konrad Beyer, Miriam Reinig, Mirko Singer, Chafen Lu, Timothy A. Springer, Friedrich Frischknecht
This study shows that the I-domain of TRAP in Plasmodium parasites mediates adhesion and that its cationic charge and polyspecificity are critical for infectivity.
bioRxiv · Sep 20, 2018 · PreprintMicrobiology