Dennis Klug

This study identifies distinct roles of TRAP and TRP1 adhesins in Plasmodium sporozoite motility and invasion, showing differential signaling requirements for gliding and transmission.

This study uses a genetic knockout of the Tan enzyme in Anopheles mosquitoes to show reduced light-dependent attraction, indicating a role for vision in behavior.

This study shows that the yellow gene in Anopheles coluzzii affects pigmentation and increases susceptibility to Plasmodium berghei through microbiota-dependent mechanisms.

This paper describes a gene drive targeting Saglin and Lipophorin in Anopheles mosquitoes to reduce Plasmodium transmission, showing successful spread in caged populations.

This study shows that the I-domain of TRAP in Plasmodium parasites mediates adhesion and that its cationic charge and polyspecificity are critical for infectivity.