Structural Design of Chimeric Antigens for Multivalent Protein Vaccines
Sarah Hollingshead, Ilse Jongerius, Rachel M. Exley, Steven Johnson, Susan M. Lea, Christoph M. Tang
This paper designs chimeric antigens for multivalent protein vaccines by combining immunogenic epitopes from integral membrane proteins with a molecular scaffold, showing efficacy in mice against meningococcal disease.
Nature Communications · Mar 7, 2018Peer-reviewedMolecular Biology