Steven Johnson

Structure of the proton-powered secretion motor at the heart of the bacterial flagellum

The paper presents cryo-EM structures of the bacterial flagellar Export Apparatus, revealing a rotary gating mechanism coupling proton flow to export channel opening.

Structural insights into mitotic-centrosome assembly

This study investigates the structural differences in mitotic-centrosome assembly between Drosophila and C. elegans, showing divergent mechanisms involving Cnn and SPD-5 proteins.

Delta C2 Domain β1-2 loop contributes to robust Notch signalling

The paper shows that the Delta C2 domain β1-2 loop is essential for phospholipid binding and robust Notch signaling in Drosophila.

Structural Design of Chimeric Antigens for Multivalent Protein Vaccines

This paper designs chimeric antigens for multivalent protein vaccines by combining immunogenic epitopes from integral membrane proteins with a molecular scaffold, showing efficacy in mice against meningococcal disease.

Structure of the Core of the Type Three Secretion System ExportApparatus

The paper determines the structure of the T3SS export gate core using cryo-EM, revealing a helical assembly with 5:4:1 stoichiometry and identifying it as a key component of the secretion channel.