Author

Alycen M. Harney

Broad InstituteORCID 0000-0002-7869-006XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alina AinbinderiD· 2 shared José C. FloreziD· 2 shared Suzanne B.R. JacobsiD· 2 shared Aaron LeongiD· 1 shared Adam Štefek· 1 shared Alham Saadat· 1 shared Amy DeikiD· 1 shared Anne Elizabeth CarpenteriD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersGenomics

Alina AinbinderORCID

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2 papers

Recent·Most cited

Discovering cellular programs of intrinsic and extrinsic drivers of metabolic traits using LipocyteProfiler

Samantha Laber, Sophie Strobel, Josep Maria Mercader, Hesam Dashti, Felipe R. C. dos Santos, Phil Kubitz, Maya Jackson, Alina Ainbinder, Julius Honecker, Saaket Agrawal, Garrett Garborcauskas, David R. Stirling, Aaron Leong, Katherine Figueroa, Nasa Sinnott-Armstrong, , Melina Claussnitzer

The paper introduces LipocyteProfiler, a high-throughput microscopy assay to profile lipid-storing cells and identifies cellular programs linked to metabolic traits like insulin resistance and lipodystrophy.

Cell Genomics · Jun 20, 2023Peer-reviewedGenomics

Mct11 deficiency alters hepatic glucose metabolism and energy homeostasis

Alina Ainbinder, Liping Zhao, Patricia Glover, Karen Gelinas-Roa, Victor Rusu, Alycen M. Harney, Eitan Hoch, Amy Deik, Kerry A. Pierce, Kevin H. Bullock, Courtney Dennis, Sarah Jeanfavre, Jesse Krejci, Jinyoung Choi, Anthony Neil Hollenberg, , Suzanne B.R. Jacobs

This study shows that Mct11 deficiency in mice disrupts hepatic glucose and lipid metabolism, mirroring T2D features, and identifies MCT11 as a potential therapeutic target for T2D.

bioRxiv · Sep 8, 2021 · PreprintGenetics