Author

Sarah K. Garcia

Vanderbilt University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Lars PlateiD· 2 shared Lea A. BarnyiD· 2 shared Aiden Houcek· 1 shared Burak UzayiD· 1 shared Ege T. KavalaliiD· 1 shared Jake N HermansoniD· 1 shared Minsoo KimiD· 1 shared Philip E. StaufferiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

Lars PlateORCID

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Author profile →

2 papers

Recent·Most cited

Proteostasis and Unfolded Protein Response Dynamics in Human Neuron and Mouse Glia Co-culture Reveal Cell-Specific Aging Responses

Lea A. Barny, Sarah K. Garcia, Aiden Houcek, Burak Uzay, Minsoo Kim, Ege T. Kavalali, Lars Plate

This study uses DIA proteomics to analyze age-related changes in proteostasis and UPR dynamics in human neurons and mouse glia co-cultures, revealing cell-type-specific aging responses.

bioRxiv · Aug 11, 2025 · PreprintBiochemistry

Dissecting Branch-Specific Unfolded Protein Response Activation in Drug-Tolerant BRAF-Mutant Melanoma using Data-Independent Acquisition Mass Spectrometry

Lea A. Barny, Jake N Hermanson, Sarah K. Garcia, Philip E. Stauffer, Lars Plate

This study identifies branch-specific UPR proteomic targets in BRAF-mutant melanoma using DIA LC-MS, revealing differential XBP1s regulation linked to drug tolerance.

Molecular & Cellular Proteomics · Jul 15, 2025Peer-reviewedSystems Biology