Nascent transcript folding plays a major role in determining RNA polymerase elongation rates
Tomasz W. Turowski, Elisabeth Petfalski, Benjamin D. Goddard, Sarah L. French, Aleksandra Helwak, David W. Tollervey
The paper investigates how nascent transcript folding and G+C-content influence RNA polymerase elongation rates in vivo and confirms these effects through in vitro experiments and a mathematical model.
Molecular Cell · Jun 24, 2020Peer-reviewedMolecular Biology