Author
Wellcome Centre for Cell BiologyORCID 0000-0002-1937-3048Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Max Müller, Lena Sophie Tittel, Elisabeth Petfalski…·Marie‐Luise Winz
The paper shows that New1 prevents ribosomal collisions and subsequent mRNA degradation in yeast by no-go decay, protecting essential genes from downregulation.
Tomasz W. Turowski, Elisabeth Petfalski, Marie‐Luise Winz, David W. Tollervey
The paper investigates transcription termination by RNA polymerase I, showing that 3-end cleavage and backtracking promote termination, with biophysical modeling suggesting ~10% premature termination.
Tomasz W. Turowski, Elisabeth Petfalski, Benjamin D. Goddard…·David W. Tollervey
The paper investigates how nascent transcript folding and G+C-content influence RNA polymerase elongation rates in vivo and confirms these effects through in vitro experiments and a mathematical model.