Independent signaling pathways provide a fail-safe mechanism to prevent tumorigenesis
Sari Anschütz, Andrea Schubert, Jobelle M. Peralta, Todd G. Nystul, Katja Rust
The paper uses single-cell transcriptomics to show that non-interacting signaling pathways prevent tumorigenesis by converging at the transcriptional level to block malignant cell behavior.
bioRxiv · Feb 28, 2025 · PreprintCancer Biology