Changes in nuclear and actin mechanics from G1 to G2 affect nuclear integrity
Samantha Bunner, Katie T. Huang, Anish Shah, Schuyler Figueroa, Nick Lang, Catherine G. Chu, Nebiyat Eskndir, Mai Pho, Gianna Manning, Mindy Zheng, Lillian K. Fritz‐Laylin, Katrina Velle, Joshua Marcus, James D. Orth, Andrew D. Stephens
This study shows that nuclear and actin mechanics change from G1 to G2, leading to decreased nuclear stiffness and increased vulnerability to rupture.
Journal of Cell Science · Jan 19, 2026Peer-reviewedCell Biology