Author

Nebiyat Eskndir

University of Massachusetts Amherst

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Andrew D. StephensiD· 2 shared Gianna Manning· 2 shared Mai Pho· 2 shared Aditi SahuiD· 1 shared Ajit J. NirmaliD· 1 shared Alexander B. AfeyaniD· 1 shared Anish Shah· 1 shared Asaf Tal· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

Andrew D. StephensORCID

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Author profile →

3 papers

Recent·Most cited

Changes in nuclear and actin mechanics from G1 to G2 affect nuclear integrity

Samantha Bunner, Katie T. Huang, Anish Shah, Schuyler Figueroa, Nick Lang, Catherine G. Chu, Nebiyat Eskndir, Mai Pho, Gianna Manning, Mindy Zheng, Lillian K. Fritz‐Laylin, Katrina Velle, Joshua Marcus, James D. Orth, Andrew D. Stephens

This study shows that nuclear and actin mechanics change from G1 to G2, leading to decreased nuclear stiffness and increased vulnerability to rupture.

Journal of Cell Science · Jan 19, 2026Peer-reviewedCell Biology

Craters on the melanoma surface facilitate tumor-immune interactions and demonstrate pathologic response to checkpoint blockade in humans

Aya Ludin, Georgia L. Stirtz, Asaf Tal, Ajit J. Nirmal, Kathleen Lindahl Pfaff, Michael P. Manos, Naomi R. Besson, Nebiyat Eskndir, Billie A. Porter, Stephanie M. Jones, Hannah Mae Faulkner, Qiyu Gong, Sophia Liu, Irving Barrera, Lijian Wu, , Leonard Ira Zon

The paper identifies crater-shaped structures in melanoma that enhance immune response to checkpoint blockade therapy in humans and zebrafish.

Cell · Oct 17, 2025Peer-reviewedCancer Biology

DNA damage causes ATM-dependent heterochromatin loss leading to nuclear softening, blebbing, and rupture

Nebiyat Eskndir, Manseeb Hossain, Marilena L. Currey, Mai Pho, Yasmin Berrada, Katie Y. Lin, Gianna Manning, Kelsey Prince, Andrew D. Stephens

This study shows DNA damage reduces heterochromatin via ATM, leading to nuclear softening, blebbing, and rupture in MEF cells.

Molecular Biology of the Cell · Dec 20, 2024Peer-reviewedCell Biology