Long-term adaptation of prefrontal circuits in a mouse model of NMDAR hypofunction
Marion Ponserre, Tudor M. Ionescu, Alessa A. Franz, Serena Deiana, Niklas Schuelert, Thorsten Lamla, Rhîannan H. Williams, Carsten Tobias Wotjak, Scott Hobson, Julien Dine, Azar Omrani
This study investigates the long-term effects of subchronic PCP treatment on prefrontal circuits in mice, revealing alterations in cognitive performance, gamma oscillations, and synaptic connectivity associated with schizophrenia endophenotypes.
Neuropharmacology · Apr 27, 2024Peer-reviewedNeuroscience