Author

Sergio Bernal-Garcia

Mortimer B. Zuckerman Mind Brain Behavior Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

Franck PolleuxiD· 2 shared Aleksandra J. RecuperoiD· 1 shared Alessandro RosaiD· 1 shared Alexa P. Schlotter· 1 shared Charlotte D’HulstiD· 1 shared Daniela Pereira· 1 shared Eugene LempertiD· 1 shared Luís R. SaraivaiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersNeuroscience

Franck PolleuxORCID

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3 papers

Recent·Most cited

SRGAP2 limits experience-dependent structural synaptic plasticity in adult cortical circuits

Sergio Bernal-Garcia, Regina Jiang, Franck Polleux

This study shows that SRGAP2 limits experience-dependent structural synaptic plasticity in adult cortical circuits, with its deletion increasing plasticity in mice and suggesting a role for human-specific paralogs in human neurons.

bioRxiv · Aug 25, 2026 · PreprintNeuroscience

RESPAN: A Deep Learning Pipeline for Accurate and Automated Restoration, Segmentation, and Quantification of Dendritic Spines

Sergio Bernal-Garcia, Alexa P. Schlotter, Daniela Pereira, Aleksandra J. Recupero, Franck Polleux, Luke Alexander Hammond

RESPAN improves dendritic spine quantification by integrating deep learning for restoration, segmentation, and analysis, achieving higher accuracy and usability than existing methods.

bioRxiv · Jun 6, 2024 · PreprintNeuroscience

Commonality of Odorant Receptor Choice Mechanism Revealed by Analysis of a Highly Represented Odorant Receptor Transgene

Melanie Makhlouf, Charlotte D’Hulst, Masayo Omura, Alessandro Rosa, Raena Mina, Sergio Bernal-Garcia, Eugene Lempert, Luís R. Saraiva, Paul G. Feinstein

The paper identifies a common mechanism for singular gene expression in odorant receptors by analyzing transgenic mice with enhanced OR1A1 expression.

bioRxiv · May 5, 2022 · PreprintNeuroscience