Unpacking bedaquiline hetero-resistance: the importance of intermediate profiles for phenotypic drug-susceptibility testing
Nabila A. Ismail, Frik A. Sirgel, Shaheed Vally Omar, Shatha Omar, Marianna de Kock, Claudia Spies, Megan Folkerts, Grant Theron, David M. Engelthaler, John Z. Metcalfe, Robin M. Warren
This paper shows that considering intermediate results in phenotypic drug susceptibility testing can detect bedaquiline heteroresistance at low frequencies, improving resistance determination.
Antimicrobial Agents and Chemotherapy · Jul 21, 2025Peer-reviewedMicrobiology