BiochemistrybioRxivPreprint
An inhibitor-interaction intermediate of HIV-1 protease, revealed by Isothermal Titration Calorimetry and NMR spectroscopy
Shahid N Khan, John D Persons, Michel Guerrero…·Rieko Ishima
The paper investigates entropy-enthalpy compensation in HIV-1 protease mutants using ITC and NMR, revealing an inhibitor-bound intermediate pathway.
DOI 10.1101/404996