Author

Shang Lou

University of Science and Technology of China

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Fan ZhangiD· 1 shared Fang Liu· 1 shared Hailong ZhaoiD· 1 shared Haishuai WangiD· 1 shared Han Li· 1 shared Han ShuiD· 1 shared Haoyi WangiD· 1 shared Hongcang GuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

Fan ZhangORCID

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2 papers

Recent·Most cited

Xenograft supervision and joint methylation-fragment-end encoding define a reusable molecular scoring layer for cell-free tumor DNA

Xuchao Zhang, Xiaojun Sun, Rui Wang, Ningning Zhao, Fang Liu, Xuhua Li, Jian Huang, Jiamin Sun, Han Li, Shang Lou, Haoyi Wang, Hailong Zhao, Han Shu, Peimeng Zhen, Hongcang Gu, , Fan Zhang

ctDNA-BERT scores individual bisulfite reads for cell-free DNA methylation analysis, achieving high accuracy in cancer staging without cohort-specific retraining.

bioRxiv · Oct 27, 2026 · PreprintBioinformatics

Systematic discovery of single-cell protein networks in cancer with Shusi

Tianyun Zhang, Jiajun Yu, Shang Lou, Zhaozhen Liang, Yue Liang, Zhekai Li, Haishuai Wang, Shanshan Pei, Ning Shen

Shusi predicts context-specific protein-protein interactions in cancer using a large language model-enhanced variational graph auto-encoder, identifying actionable vulnerabilities in acute myeloid leukemia.

bioRxiv · Apr 27, 2025 · PreprintBioinformatics