Author

Han Li

Howard Hughes Medical Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Bei LiuiD· 1 shared Cheng‐Wei JuiD· 1 shared Chuan HeiD· 1 shared Erica L. NiewoldiD· 1 shared Fan ZhangiD· 1 shared Fang Liu· 1 shared Hailong ZhaoiD· 1 shared Han ShuiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCell Biology

Bei LiuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Xenograft supervision and joint methylation-fragment-end encoding define a reusable molecular scoring layer for cell-free tumor DNA

Xuchao Zhang, Xiaojun Sun, Rui Wang, Ningning Zhao, Fang Liu, Xuhua Li, Jian Huang, Jiamin Sun, Han Li, Shang Lou, Haoyi Wang, Hailong Zhao, Han Shu, Peimeng Zhen, Hongcang Gu, , Fan Zhang

ctDNA-BERT scores individual bisulfite reads for cell-free DNA methylation analysis, achieving high accuracy in cancer staging without cohort-specific retraining.

bioRxiv · Oct 27, 2026 · PreprintBioinformatics

ProMeta: A meta-learning framework for robust disease diagnosis and prediction from plasma proteomics

Han Li, Haoteng Gu, LH Hu, Zimo Zhang, Yongji Lv, Peng Gao, Johnathan Cooper‐Knock, Yaosen Min, Jianyang Zeng, Sai Zhang

ProMeta improves disease diagnosis and prediction from plasma proteomics using a meta-learning framework that overcomes data scarcity with biological priors and interpretable features.

Bioinformatics · Jul 1, 2026Peer-reviewedBioinformatics

A U1-U3 snRNA-snoRNA interaction couples SF3B1 mutation to chromatin-state rewiring and genome instability

Peng Xia, Han Li, Yiyi Ji, Cheng‐Wei Ju, Yiqian Pan, Jing Mo, Xuanhao Zhu, Lijie Zhao, Ruitu Lyu, Erica L. Niewold, Mike Fernandez, Yuxi Ai, Jiangbo Wei, Robert K. Bradley, Lili Wang, , Chuan He

This paper identifies a U1-U3 snRNA-snoRNA interaction that links SF3B1 mutations to chromatin-state changes and genome instability, with therapeutic potential through antisense oligonucleotides.

bioRxiv · Jun 8, 2026 · PreprintCell Biology