Myofibroblasts reduce angiogenesis and vasculogenesis in a vascularized microphysiological model of lung fibrosis
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Cam Thai, Shania Dantes, David Allen Barbie, Sarah E. Shelton, Roger Dale Kamm
The paper develops a microphysiological model of lung fibrosis to study myofibroblast-vascular interactions, finding that myofibroblasts reduce angiogenesis and vasculogenesis through TGF-β1 and reduced VEGF.
Advanced Functional Materials · Dec 30, 2025Peer-reviewedBioengineering