BioengineeringbioRxivPreprint
A mechanically actuated lung microvascular model reveals that breathing-like deformation enhances tumor cell extravasation
Marie A. Floryan, Roland M. Stoll, Ingmar Fleps…·Elena Cambria
DOI 10.64898/2026.09.17.752385
Author
Elena Cambria
Massachusetts Institute of TechnologyORCID 0000-0001-6896-5421Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2025-2026 · peak 2/yrCo-Author Collaboration Network
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Curved chords = mutual co-authorship4 papers
Recent·Most cited
- BioengineeringBiofabricationPeer-reviewed
IntravChip: a vascularized and perfused microfluidic model of the primary tumor microenvironment to collect intravasated tumor cells
Marie A. Floryan, Alessandro Cordiale, Heather Jensen…·Roger Dale Kamm
The paper introduces IntravChip, a microfluidic platform to study tumor cell intravasation and collect intravasated cells, showing it can quantify intravasation rates and test anti-metastatic drugs.
2 citations - BioengineeringAdvanced Functional MaterialsPeer-reviewed
Myofibroblasts reduce angiogenesis and vasculogenesis in a vascularized microphysiological model of lung fibrosis
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko…·Roger Dale Kamm
The paper develops a microphysiological model of lung fibrosis to study myofibroblast-vascular interactions, finding that myofibroblasts reduce angiogenesis and vasculogenesis through TGF-β1 and reduced VEGF.
1 citation - Biophysicsnpj Biological Physics and Mechanics.Peer-reviewed
Remodeling of self-assembled microvascular networks under long term flow
Marie A. Floryan, Elena Cambria, Adriana Blazeski…·Roger Dale Kamm
This study shows that long-term flow can maintain and remodel microvascular networks in a microphysiological system for 51 days, reducing inflammation and enabling vascular remodeling.
21 citationstop 3%