Developmental BiologybioRxivPreprint
Blood originates in hypoblasts during embryonic development
Yiming Chao, Hongji Li, Lu Liu…·Ryohichi Sugimura
The paper identifies hypoblasts as the origin of the first blood cells in human and non-human primate embryos, showing they contribute to hemoglobin+ phagocyte-like cells and sustain oxygen levels before heart formation.
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