Author

Degong Ruan

University of Hong Kong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:non-human primate· 1

Frequent Co-Authors

Guocheng LaniD· 1 shared Hongji Li· 1 shared Lu LiuiD· 1 shared Pengtao LiuiD· 1 shared Ryohichi SugimuraiD· 1 shared Shao Jie Xu· 1 shared Shihui ZhangiD· 1 shared Xiaolin XuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

Guocheng LanORCID

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1 paper

Recent·Most cited

Blood originates in hypoblasts during embryonic development

Yiming Chao, Hongji Li, Lu Liu, Zhengyi Tay, Shihui Zhang, Xiaolin Xu, Shao Jie Xu, Yang Xiang, Degong Ruan, Yuanhua Huang, Guocheng Lan, Pengtao Liu, Ryohichi Sugimura

The paper identifies hypoblasts as the origin of the first blood cells in human and non-human primate embryos, showing they contribute to hemoglobin+ phagocyte-like cells and sustain oxygen levels before heart formation.

bioRxiv · Nov 7, 2025 · PreprintDevelopmental Biology