Hydroxysteroid 17-beta dehydrogenase 13 (Hsd17b13) knockdown attenuates liver steatosis in high-fat diet obese mice
Shehroz Mahmood, Nicola Morrice, Dawn Thompson, Sara Milanizadeh, Sophie Wilson, Phillip D. Whitfield, George D. Mcilroy, Justin J. Rochford, Nimesh Mody
This study shows that knocking down Hsd17b13 in obese mice reduces liver steatosis and improves liver health markers, suggesting HSD17B13 as a therapeutic target for MASLD.
Experimental Physiology · Feb 27, 2025Peer-reviewedPhysiology