Author

George D. Mcilroy

University of AberdeenORCID 0000-0003-4230-4355Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Justin J. RochfordiD· 3 shared Ahlima RoumaneiD· 2 shared Mansi TiwariiD· 2 shared Nadine SommeriD· 2 shared Weiping HaniD· 2 shared Dawn ThompsoniD· 1 shared Lora K. HeisleriD· 1 shared Mirela DelibegovićiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersPhysiology

Justin J. RochfordORCID

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3 papers

Recent·Most cited

PhysiologybioRxivPreprintApr 7, 2026

AAV-mediated delivery of leptin but not adiponectin improves metabolic health in a mouse model of congenital generalised lipodystrophy

Nadine Sommer, Ahlima Roumane, Mansi Tiwari…·Justin J. Rochford

This study evaluates AAV-mediated delivery of leptin and adiponectin in a mouse model of congenital generalized lipodystrophy, finding that leptin improves metabolic health while adiponectin does not.

DOI 10.64898/2026.04.07.716869

mouseexperimental assay

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PhysiologyExperimental PhysiologyPeer-reviewedFeb 27, 2025

Hydroxysteroid 17-beta dehydrogenase 13 (Hsd17b13) knockdown attenuates liver steatosis in high-fat diet obese mice

Shehroz Mahmood, Nicola Morrice, Dawn Thompson…·Nimesh Mody

This study shows that knocking down Hsd17b13 in obese mice reduces liver steatosis and improves liver health markers, suggesting HSD17B13 as a therapeutic target for MASLD.

14 citationstop 3%

mousebulk RNA-seq

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Molecular BiologyGene TherapyPeer-reviewedJul 28, 2024

Preclinical evaluation of tissue-selective gene therapies for congenital generalised lipodystrophy

Mansi Tiwari, Ahlima Roumane, Nadine Sommer…·George D. Mcilroy

This paper evaluates tissue-selective AAV gene therapy for lipodystrophy in mice, finding that adipose-targeted vectors improve metabolic health without liver expression.

6 citations

mouseexperimental assay

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