Author

Dawn Thompson

University of AberdeenORCID 0000-0003-0948-9458Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Florentina NegoitaiD· 1 shared George D. McilroyiD· 1 shared James N. HislopiD· 1 shared Justin J. RochfordiD· 1 shared Kei SakamotoiD· 1 shared Kristina Hellberg· 1 shared Kyle Thompson· 1 shared Max Gardner· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Florentina NegoitaORCID

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2 papers

Recent·Most cited

Cell BiologyBiochemical JournalPeer-reviewedAug 20, 2026

Substrate-specific regulation of the mTORC1 pathway by G protein-coupled receptors

Samuel J. Atkinson, Florentina Negoita, Yuichiro Ioi…·Riko Hatakeyama

This study shows that GPCRs regulate mTORC1 substrates differently, with M5R promoting protein synthesis while allowing lysosome biogenesis.

DOI 10.1042/bcj20260165

proteomicsexperimental assay

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PhysiologyExperimental PhysiologyPeer-reviewedFeb 27, 2025

Hydroxysteroid 17-beta dehydrogenase 13 (Hsd17b13) knockdown attenuates liver steatosis in high-fat diet obese mice

Shehroz Mahmood, Nicola Morrice, Dawn Thompson…·Nimesh Mody

This study shows that knocking down Hsd17b13 in obese mice reduces liver steatosis and improves liver health markers, suggesting HSD17B13 as a therapeutic target for MASLD.

14 citationstop 3%

mousebulk RNA-seq

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