Justin J. Rochford

This study evaluates AAV-mediated delivery of leptin and adiponectin in a mouse model of congenital generalized lipodystrophy, finding that leptin improves metabolic health while adiponectin does not.

This study quantifies adipocyte morphology changes in breast tissue across cancer pathologies and risk factors, finding size differences in cancer-associated adipocytes (CAAs) linked to menopausal status, BMI, and survival.

This study shows that knocking down Hsd17b13 in obese mice reduces liver steatosis and improves liver health markers, suggesting HSD17B13 as a therapeutic target for MASLD.

This paper evaluates tissue-selective AAV gene therapy for lipodystrophy in mice, finding that adipose-targeted vectors improve metabolic health without liver expression.