Author

Sheng Liu

Michigan State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Genomics· 2 Neuroscience· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Antonio White· 2 shared Charlotte Best· 2 shared Harikesh DubeyiD· 2 shared Rebecca Christine KnickmeyeriD· 2 shared Alexander L. CarlsoniD· 1 shared Ann Alex· 1 shared Bi-Kun Xiao· 1 shared Bo ZhongiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersNeuroscience

Antonio White

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Fentanyl and fentanyl-xylazine co-exposure influence mitochondrial transcriptional programs in human trophoblasts

Jiayu Meng, Lei Liu, Sheng Liu, Keyi Huang, Yoel Sadovsky, Yingshi Ouyang

This study examines how fentanyl and fentanyl-xylazine co-exposure affect mitochondrial transcription in human trophoblasts, showing suppression in syncytiotrophoblasts and discordant regulation with FMX.

bioRxiv · Nov 2, 2026 · PreprintGenomics

An additional site mutation in MITA/STING gain-of-function mutants abolishes the autoimmune SAVI phenotypes and directs a therapeutic strategy.

Fang-Xu Li, Sheng Liu, Zhi-Dong Zhang, Xin Shuai, Bi-Kun Xiao, Jia Yang, Defen Lu, Dandan Lin, Guijun Shang, Bo Zhong

This study identifies a mutation that suppresses SAVI phenotypes in MITA/STING gain-of-function mutants and proposes a therapeutic strategy using a peptide inhibitor.

Cell Insight · Jan 8, 2026Peer-reviewedImmunology

Myelin Decompaction in Mice Given Anesthetics during Magnetic Resonance Imaging

Charlotte Best, Harikesh Dubey, Sheng Liu, Antonio White, Sravya Jayam, Christiane L. Mallett, Rebecca Christine Knickmeyer

The paper examines if prolonged anesthetic exposure during MRI increases myelin decompaction in mice, finding significantly higher proportions in anesthetized mice.

bioRxiv · Jul 29, 2025 · PreprintNeuroscience

Effect of Human Infant Gut Microbiota on Mouse Behavior, Dendritic Complexity, and Myelination

Harikesh Dubey, Rohon Roychoudhury, Ann Alex, Charlotte Best, Sheng Liu, Antonio White, Alexander L. Carlson, M. Andrea Azcárate-Peril, Linda S. Mansfield, Rebecca Christine Knickmeyer

This study investigates how human infant gut microbiota affects mouse behavior, myelination, and dendritic morphology, finding that humanized mice show altered brain development compared to germ-free controls.

bioRxiv · Oct 24, 2023 · PreprintNeuroscience

HuluFISH non-denaturing in situ detection of genomic DNA opened by CRISPR-Cas9 Nickase and Exonuclease

Kang Han, Sheng Liu, Yong-Sheng Cheng

The paper introduces a method to detect small genomic loci using CRISPR-Cas9 nickase and exonuclease to open DNA for FISH without heat denaturation.

bioRxiv · Dec 23, 2021 · PreprintGenomics