Author

Shengwen Wang

Qilu Pharmaceutical Co., Ltd. (China)Primary ORCID profile (0000-0002-2744-3085 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Shengwen WangiD2 papers · Shanghai Jiao Tong University

Biology Disciplines

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Bioengineering· 2 Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 4 Approach:experimental assay· 4 Organism:non-human primate· 4

Frequent Co-Authors

Hao LiiD· 4 shared Mengmeng YuiD· 4 shared Rui HeiD· 4 shared Xianggang Xu· 4 shared Youguang Luo· 4 shared Zhenhua WangiD· 4 shared Zhenming An· 4 shared Bo Sun· 3 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersBioengineering

Hao LiORCID

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4 papers

Recent·Most cited

Novel Muscle-Tropic AAV Capsids with Dramatically Enhanced Transduction and Safety Profiles in Non-Human Primates

Youguang Luo, Linlin Zhang, Zhenhua Wang, Hao Li, Rui He, Xiaofei Lv, Xianggang Xu, Shengwen Wang, Zhen Sun, Mengmeng Yu, Qun Zhang, Peilu Zhao, Long Wang, Bo Sun, Daoyuan Li, Zhenming An

The paper engineers AAV capsids with improved muscle transduction and reduced off-target distribution in non-human primates using the REACH platform.

bioRxiv · May 26, 2026 · PreprintBioengineering

Identification of AAV Capsids with Enhanced Intravitreal Transduction and Favorable Safety Profile in Non-Human Primates

Zhenhua Wang, Hao Li, Zhen Sun, Xianggang Xu, Qun Zhang, Peilu Zhao, Long Wang, Tongqian Xiao, Mengmeng Yu, Shengwen Wang, Rui He, Can Hu, Daoyuan Li, Bo Sun, Linlin Zhang, , Zhenming An

The paper identifies AAV capsid variants with improved intravitreal transduction and safety in non-human primates.

bioRxiv · Apr 24, 2026 · PreprintBioengineering

Novel Engineered AAV Variants Demonstrate Superior Blood-Brain Barrier Penetration and Safety in Non-Human Primates

Zhenhua Wang, Hao Li, Xianggang Xu, Z. P Sun, Rui He, Linlin Zhang, Mengmeng Yu, Shengwen Wang, Can Hu, Lei Liu, Lele Ren, Yanling Xu, Tongqian Xiao, Daoyuan Li, Bo Sun, , Zhenming An

The paper develops novel AAV variants with improved BBB penetration and safety in NHPs, showing higher brain transduction and reduced organ toxicity.

bioRxiv · Apr 1, 2026 · PreprintNeuroscience

LRP6-Guided Engineering of AAV9 Variants with Enhanced Blood-Brain Barrier Penetration and Reduced Liver Tropism in Non-Human Primates

Zhenhua Wang, Xianggang Xu, Zhen Sun, Hao Li, Rui He, Yanling Xu, Mengmeng Yu, Shengwen Wang, Can Hu, Lei Liu, Lele Ren, Li Zhang, Tongqian Xiao, Youguang Luo, Zhenming An

This study engineers AAV9 variants guided by LRP6 to enhance BBB penetration and reduce liver tropism in non-human primates.

bioRxiv · Mar 18, 2026 · PreprintNeuroscience