Author
Qilu Pharmaceutical Co., Ltd. (China)ORCID 0000-0001-8656-0188Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Youguang Luo, Linlin Zhang, Zhenhua Wang…·Zhenming An
The paper engineers AAV capsids with improved muscle transduction and reduced off-target distribution in non-human primates using the REACH platform.
Zhenhua Wang, Hao Li, Zhen Sun…·Zhenming An
The paper identifies AAV capsid variants with improved intravitreal transduction and safety in non-human primates.
Zhenhua Wang, Hao Li, Xianggang Xu…·Zhenming An
The paper develops novel AAV variants with improved BBB penetration and safety in NHPs, showing higher brain transduction and reduced organ toxicity.
Zhenhua Wang, Xianggang Xu, Zhen Sun…·Zhenming An
This study engineers AAV9 variants guided by LRP6 to enhance BBB penetration and reduce liver tropism in non-human primates.
Mengmeng Yu, Yuxing Qu, Liuke Sun…·Xiaojun Wang
This study identifies PPM1G as a host phosphatase that regulates influenza vRNP homeostasis by modulating NP phosphorylation and autophagy.
Liuke Sun, Yuxing Qu, Xuefeng Wang…·Xiaojun Wang
This study identifies functional determinants in chicken ANP32A that enable species-specific support of avian influenza virus polymerase.
Liuke Sun, Xing Yuan Guo, Mengmeng Yu…·Xiaojun Wang
This study shows that human ANP32A/B are SUMOylated, enabling avian influenza virus NS2 to enhance polymerase activity and overcome species-specific restrictions.