The annexin A1 mimetic peptide Ac2-26 promotes inflammation-resolution and stimulates skeletal muscle regeneration in the mdx mouse model of Duchenne muscular dystrophy
Hafiz Javed ur Rehman, Xinyue Lu, Savannah M. Nasrallah, Binayok Sharma, Sophie A. Lies, Shikha Adhikari, Steven S. Welc, James F. Markworth
This study shows that the ANXA1 mimetic peptide Ac2-26 reduces inflammation and improves skeletal muscle regeneration in mdx mice, offering a potential steroid-sparing therapy for DMD.
bioRxiv · Oct 6, 2026 · PreprintCell Biology