NeurosciencebioRxivPreprint
Intrinsic and TDP-43 dysfunction-induced catabolic stress elicit neuroprotective cellular degradation in ALS-vulnerable motor neurons
Kazuhide Asakawa, Takuya Tomita, Shinobu Shioya…·Koichi Kawakami
The paper identifies large spinal motor neurons as highly autophagic and shows that their enhanced degradation is neuroprotective in ALS.
DOI 10.1101/2025.05.06.652552